Polymorphisms in the bovine tumour necrosis factor receptor type two gene (TNF-RII) and cell subpopulations naturally infected with bovine leukaemia virus
نویسندگان
چکیده
منابع مشابه
Α-lactalbumin Gene and Susceptibility of Lymphocytes to Infections with Bovine Leukaemia Virus and to Apoptosis in Naturally Infected Cows
A study was undertaken to analyse the effect of polymorphism of α-lactalbumin (ALA) gene at position -1689 on the susceptibility of lymphocytes to the infection with bovine leukaemia virus (BLV) and to undergoing apoptosis during the first three months after calving. The experiments covered 97 Black-and-White breed cows, aged 3–8 years, from three herds. The infection with BLV was diagnosed on ...
متن کاملBovine leukaemia virus and enzootic bovine leukosis.
Infection of bovines with bovine leukaemia virus (BLV) manifests itself in either of two ways: 30-70% of carriers develop persistent lymphocytosis (PL), with the viral genome integrated at a large number of different sites in the DNA of the affected B-lymphocytes, without causing any chromosomal abnormalities. Only 0,1-10% of carriers develop lymphoid tumours, which also consist of B-lymphocyte...
متن کاملInduction and inhibition of bovine leukaemia virus expression in naturally infected cells.
Bovine leukaemia virus (BLV) resides in infected lymphocytes in a latent, repressed state but becomes expressed a few hours after the cells are cultured in vitro. We have identified several conditions and factors affecting the expression of BLV in short-term cultures of naturally infected lymphoid cells. The presence of foetal calf serum in the culture medium greatly stimulates virus expression...
متن کاملRelationship of bovine TNF-α gene polymorphisms with the risk of bovine tuberculosis in Holstein cattle
Many studies suggest significant genetic variation in the resistance of cattle and humans to infection with Mycobacterium bovis (M. bovis), the causative agent of zoonotic tuberculosis. TNF-α promotes inflammation and induces apoptosis in response to mycobacterial infection. The aim of the present study was to investigate the influence of single nucleotide polymorphisms of the TNF-α gene on bov...
متن کاملPolymorphism in the promoter region of the tumor necrosis factor-alpha gene in cattle herds naturally infected and uninfected with the bovine leukemia virus.
The objective of this study was to describe and compare the genetic structure (TNF-alpha -position 824) of dairy cattle herds infected and not infected with the bovine leukemia virus (BLV). The results of the present study indicate that BLV-positive herds were characterized by similar genetic structure (TNF-alpha -824A/G). The genetic equilibrium in these herds was preserved, but a tendency to ...
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ژورنال
عنوان ژورنال: Journal of Veterinary Research
سال: 2019
ISSN: 2450-8608
DOI: 10.2478/jvetres-2019-0032